SCENIC+: single-cell multiomic inference of enhancers and gene regulatory networks

Joint profiling of chromatin accessibility and gene expression of individual cells provides an opportunity to decipher enhancer-driven gene regulatory networks (eGRN).

Carmen Bravo González-Blas^1,2,* Seppe De Winter^1,2,* Gert Hulselmans^1,2, Nikolai Hecker^1,2, Irina Matetovici^1,3, Valerie Christiaens^1,2, Suresh Poovathingal¹, Jasper Wouters^1,2, Sara Aibar^1,2 and Stein Aerts^1,2,#
1 VIB Center for Brain & Disease Research, Leuven, Belgium
² Department of Human Genetics, KU Leuven, Leuven, Belgium
³ VIB Tech Watch, VIB Headquarters, Ghent, Belgium
^# Corresponding author: stein.aerts@kuleuven.be
^* These authors contributed equally
doi: https://doi.org/10.1101/2022.08.19.504505
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